Organosulfur Compounds
Medchemexpress LLC Nourseothricin sulfate (streptothricin sulfate) | 96736-11-7 | 99.9% | 100 MG
Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for Fonsecaea pedrosoi. It inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi, and can also be used as a selective marker for a wide range of organisms including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys the outer membrane of Gram-negative bacteria
- Dominant selective marker for Fonsecaea pedrosoi
- Inhibits protein biosynthesis in prokaryotic cells
- Strongly inhibits the growth of eukaryotes like fungi
- Can be used as a selective marker for bacteria, yeast, filamentous fungi, and plant cells
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | MFCD00078044 | 98.1% | 1 ML
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily utilized in neurological disease research, targeting drug metabolites and γ-secretase.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Targeted for drug metabolite research
- Used in neurological disease studies
AdipoGen Prosulfocarb sulfoxide
Chemical. CAS 51954-81-5. Formula C14H21NO2S. MW 267.39. Metabolite of the herbicide Prosulfocarb. Can be used as a reference compound.
Medchemexpress LLC Sulindac sulfone | 59973-80-7 | 98.1% | 5 MG
Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. It inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is utilized in cancer research.
- Cytotoxicity against human COLO320 cells after 72 hrs by WST-1 assay (IC50 > 200 μM)
- Cytotoxicity against human MIAPaCa2 cells after 72 hrs by WST-1 assay (IC50 > 200 μM)
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | MFCD00869764 | 99.88% | 250 MG
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. It can be used for researching Alzheimer's disease.
- Potent γ-secretase modulator (GSM).
- Selectively reduces Aβ42 production.
- Useful for Alzheimer's disease research.
Medchemexpress LLC Sulindac sulfide | 49627-27-2 | 98.10% | 250 MG
Sulindac sulfide is a noncompetitive γ-secretase inhibitor, demonstrating an IC50 of 20.2 μM for γ42-secretase activity. This compound is primarily used in research, especially for studying neurological diseases.
- Noncompetitive γ-secretase inhibitor
- IC50 of 20.2 μM for γ42-secretase activity
- Suitable for research applications
- Useful for studying neurological diseases
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.47% | C24H28N2O3 | 100 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM). It is intended for research use only.
- Available as a solid, white to off-white in color.
- Soluble in DMSO at 100 mg/mL.
- Shipped at room temperature in continental US.
Medchemexpress LLC GLP-1R modulator C5 | 421578-93-0 | 99.8% | C24H21NO3 | 100 MG
GLP-1R modulator C5 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 1.59 ± 0.53 μM). It is intended for research use only.
- Allosteric modulator
- Enhances GLP-1 binding to GLP-1R
- Suitable for research applications
- Targets glucagon receptor (GCGR)
- Relevant for inflammation or immune system disease research
- Relevant for metabolic or endocrine disease research
- Relevant for digestive system disease research
Medchemexpress LLC Mutant p53 modulator-1 | 2746371-35-5 | 99.89% | C27H32F4N8O2 | 100 MG
Mutant p53 modulator-1 is a compound that modulates mutant p53. It has been shown to reduce the progression of various cancers characterized by p53 mutations.
- Functions as a modulator for mutant p53.
- Aids in reducing the progression of cancers with p53 mutations.
- Available in both solid and solution forms for research applications.
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.5% | C24H28N2O3 | 25 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
- Enhances GLP-1 binding to GLP-1R
- Functions as an allosteric modulator
- Acts via a transmembrane site
- Molecular weight: 392.49
- Appearance: solid, white to off-white
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In-solvent storage: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO: 100 mg/mL (254.78 mM)
Medchemexpress LLC MicroRNA modulator-2 | 438599-31-6 | 99.5% | 432.49 g·mol⁻¹ | C23H20N4O3S | 10 MG
MicroRNA modulator-2 is an oxadiazole-class small molecule inhibitor of microRNA-21 (miR-21) with an AC50 of 16.48 μM. Supplied as a solid for research use, it is intended for in vitro miRNA inhibition studies and related cancer research. Molecular formula C23H20N4O3S; molecular weight 432.49 g·mol⁻¹.
- Oxadiazole-class small molecule inhibitor of miR-21.
- AC50 16.48 μM in reported assays.
- High purity (≈99.5%).
- Supplied as a solid; common size 10 mg.
- Suitable for in vitro cellular and biochemical miRNA studies.
- Store at -20°C; for research use only.
Medchemexpress LLC IL-17 modulator 4 | 2446803-65-0 | >99.0% | C27H34N6O2 | 1 ML
IL-17 modulator 4 is a proagent of IL-17 modulator 1, active against IL-17A mediated diseases. This orally active modulator shows promise for the research of conditions including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome. It inhibits IL-17A-mediated signaling pathways by stabilizing the IL-17A dimer and preventing its binding to the IL-17RA receptor.
- Modulates IL-17A protein-protein interaction
- Stabilizes IL-17A dimer conformation
- Prevents IL-17A from binding to IL-17RA receptor
- Inhibits IL-17A-mediated signaling pathways
- Exhibits good pharmacokinetic properties in rat models
- Oral bioavailability of 100% in rat models